Caleb Dillingham

Caleb Dillingham

  • Graduate Student

Epigenetic mechanisms of somatic cell reprogramming.

Sridharan Lab

The main scientific focus of the lab is in defining how the epigenome controls cell identity. We want to know how non-genetic information controls functional specialization of a cell and use this knowledge to direct efficient conversion of desired cell types with the ultimate goal of improving stem cell based therapy.

Denu Lab

Investigating the mechanism and biological function of reversible protein modifications involved in modulating signal transduction, chromatin dynamics, and gene activation and addressing the “Histone Code” hypothesis by beginning to understand histone modification signaling code and its mechanisms and regulation.

Yiming Qin

Yiming Qin

  • Graduate Student

Mitochondrial protein acetylation

Brittany Baur

Brittany Baur

  • Postdoctoral Associate

Predicting long-range enhancer-promoter interactions

Coral Wille

Coral Wille

  • Postdoctoral Associate

Epigenetic barriers of reprogramming somatic cells to induced pluripotent stem cells

Xuehua Zhong

Associate Professor

  • WID Faculty

Epigenetic regulation of plant traits and environmental adaptation.

John Denu

Professor, Multi-Omics Leader

  • WID Faculty

Epigenetic chromatin changes that regulate cell signaling and metabolism

Multi-Omics Hub

The Multi-Omics Hub will focus on the use of big data about the genes, microorganisms, and metabolites to understand biological systems. WID’s expertise makes it an ideal home for the Epigenetics Initiative for the large campus community that studies the epigenome, and as such WID will organize meetings, seminars, mutli-PI …

Connecting the Dots: a New Method to Understand Cell Type Transitions

Wisconsin Institute for Discovery (WID) researchers Rupa Sridharan and Sushmita Roy are combining their expertise in regenerative biology and computational biology to better understand how cells transition from one type to another through gene regulation.

Rupa Sridharan

Rupa Sridharan

Associate Professor

  • WID Faculty

Epigenetic control of cell identity in pluripotency, development and disease