Beyond genetics: Ideas from a flowering plant
Xuehua Zhong, Assistant Professor in WID’s Epigenetics Theme studies the epigenetic connections mammals share with plants.
Tag: epigenetics
Epigenetics researchers at WID examine how the epigenome — the layer of chemical information that sits on top of the genome — switches genes ‘on’ or ‘off’ and is controlled by outside factors such as lifestyle and diet. Research in this area focuses on the molecular, chemical, and physical components underlying epigenetic mechanisms and utilizes genomic, proteomic, and biochemical methods to reveal novel epigenetic information and mechanisms. We are investigating how extrinsic factors (diet, small-molecules, metabolism and environmental factors) influence the epigenome and control cellular decision and are developing new technologies to uncover and interrogate the epigenetic code written in chemical tags.
As part of WID’s Multi-Omics Hub, the Epigenetics Initiative reaches out to foster interdisciplinary collaborations with basic and translational research in epigenetics and chromatin function.
Cracking the (Zip)code of Neural Cells
Published today in Stem Cell Reports, researchers led by Randolph Ashton and Ethan Lippmann present a unifying protocol to create neural stem cells from diverse regions of the hindbrain and spinal cord.
Flipping the Switch on Pluripotent Stem Cells
Rupa Sridharan, Assistant Professor of Cell and Regenerative Biology at Wisconsin Institute for Discovery explains how she increased reprogramming efficiency to get pluripotent stem cells.
Growing Epigenetics Community Gives “Nurture” Deepened Meaning
At the first Midwest Chromatin and Epigenetics Meeting, WID researchers and scientists around the country are giving new meaning to the “Nature versus Nurture” debate.
Fatty Acids Like Omega-3 Play a Role in Our Genes
How do fatty acids such as omega-3 play a role in human health? WID researchers are looking to the genome for answers.
WID Researcher Looks to Break Conversion Rate of Stem Cells
Epigenetics scientist Rupa Sridharan received the Shaw Scientist Award for her work in converting stem cells.
Epigenetics Group Grabs Two Best-of-Year Papers
Research led by Epigenetics researcher John Denu has gained two best-of-the-year awards from the Journal of Biological Chemistry.
Scientists Create Road Map to Metabolic Reprogramming for Aging
A recent WID study creates a better understanding of how cells are “reprogrammed” when an organism eats fewer calories.