Shaoqin (Sarah) Gong
Kellett Mid-Career Award 2018-2023
Vilas Distinguished Achievement Professor
Advancing Vision Science Chair Professor
Creating nanomedicines and nanomaterials for human health and sustainable energy applications.
Tag: gene editing
The advent of the CRISPR-CAS9 technique gives researchers the ability to make precise changes to the DNA of, theoretically, any living organism that has DNA. That precision is particularly meaningful for treatment of diseases caused by well-known faults in genes — otherwise incurable diseases such as sickle cell anemia, the fatal lung disorder cystic fibrosis, and the blindness-causing Leber congenital amaurosis. CRISPR-Cas9 could be a way to prevent or reverse those disorders.
Rupa Sridharan
Associate Professor
Epigenetic control of cell identity in pluripotency, development and disease
Krishanu Saha
Associate Professor
Human cell engineering including CRISPR gene editing and epigenetic reprogramming; science & society
Katie Mueller
In vitro modeling of CAR T cell cytotoxicity, activation, and exhaustion.
Watching gene editing at work to develop precision therapies
Kris Saha illuminates the inner workings of gene editing.
Smart Cancer Therapies: Teaching the Body’s Own T-cells to Attack Tumors
Kris Saha with colleagues David Beebe and Christian Capitini aim to develop improved methods for making CAR T-Cells with a two-year grant from the NSF.
Tools for Discovery: Srikanth Pilla
Tools for Discovery is a monthly profile series that inspects the computer programs, gadgets and methods behind WID’s ideas and discoveries.
Prof. Kris Saha quoted in LA Times story on CRISPR
New genome editing technique can target single letters of DNA sequence.
High-Content Analysis of CRISPR-Cas9 Gene-Edited Human Embryonic Stem Cells
Kris Saha and colleagues from the BIONATES Theme detail a new approach that can refine gene editing in this month’s issue of Stem Cell Reports.
Alleles in Allegro: Accelerating the Pace with HCA
Kris Saha, Assistant Professor in the BIONATES theme, is featured in a Genetic Engineering & Biotechnology News article for his work with High Content Analysis.
CRISPR Democracy: Gene Editing and the Need for Inclusive Deliberation
Assistant Professor and BIONATES theme PI Krishanu Saha along with J. Benjamin Hurlbut, Assistant Professor, Human Dimensions at Arizona State University and Sheila Jasanoff, Professor of Science and Technology at Harvard University co-authored a recent article for Issues in Science and Technology making the case for how far scientists should go in researching and applying CRISPR to editing the human germline.
A Prudent Moratorium on Editing Our Genes
Krishanu Saha, principal investigator in BIONATES, along with Sheila Jasanoff of the Harvard Kennedy School and J. Benjamin Hurlbut from Arizona State University weigh in on moratoriums for germline gene engineering for this Guardian op-ed piece.
Tools for Discovery: Sushmita Roy
Systems Biology scientist Sushmita Roy finds and predicts trends in biological networks. Her toolkit includes computer science programs, blogs and other bright minds in the Discovery Building.