Failure is often seen as a setback—but in science and entrepreneurship, it can be the spark that drives breakthroughs. In this first installment of our Productive Failure Mini-Series, explore how missteps, unexpected results, and strategic pivots shape discovery, strengthen ideas, and fuel innovation. Through real-world examples from the laboratory and the startup landscape, this conversation reveals how embracing uncertainty and learning from what doesn’t work can open the door to transformative success.