Eric Armstrong

Eric Armstrong
Comparative metabolomics; Epigenetics of therapy-resistant prostate cancer

Years at WID

2015 - present

About

Eric’s background is in the cell & molecular biology of cancer and its response to radiation and targeted therapies, including acquired resistance. His research in the Denu lab centers around mass-spectrometric analysis of metabolites and histone post-transcriptional modifications.

Education

  • B.A., honors Psychology and Biology, Gustavus Adolphus College
  • M.S., Oncology, University of Wisconsin–Madison

Research Description

Eric’s background is in the cell & molecular biology of cancer and its response to radiation and targeted therapies, including acquired resistance. His research in the Denu lab centers around mass-spectrometric analysis of histone post-transcriptional modifications.

Affiliations

  • American Association for Cancer Research
  • The American Society for Biochemistry and Molecular Biology

Selected Publications

  • S Deota, T Chattopadhyay, D Ramachandran, E Armstrong, B Camacho, B Maniyadath, A Fulzele, A Gonzalez-de-Peredo, JM Denu, U Kolthur-Seetharam, Identification of a Tissue-Restricted Isoform of SIRT1 Defines a Regulatory Domain that Encodes Specificity. Cell Rep. 2017 Mar 28;18(13):3069-3077 [PubMed: 28355560]
  • Zachary S Morris, Jamey P Weichert, Jarob Saker, Eric A Armstrong, Abigail Besemer, Bryan Bednarz, Randall J Kimple, Paul M Harari, Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer model systems. Radiother Oncol: 2015; [PubMed:26123834]
  • Randall J Kimple, Paul M Harari, Alexandra D Torres, Robert Z Yang, Benjamin J Soriano, Menggang Yu, Eric A Armstrong, Grace C Blitzer, Molly A Smith, Laurel D Lorenz, Denis Lee, David T Yang, Timothy M McCulloch, Gregory K Hartig, Paul F Lambert Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts. Clin. Cancer Res.: 2013, 19(4);855-64 [PubMed:23251001]
  • Shyhmin Huang, Chimera R Peet, Jarob Saker, Chunrong Li, Eric A Armstrong, Michael Kragh, Mikkel W Pedersen, Paul M Harari Sym004, a novel anti-EGFR antibody mixture, augments radiation response in human lung and head and neck cancers. Mol. Cancer Ther.: 2013, 12(12);2772-81 [PubMed:24130052]
  • Sergio Benavente, Shyhmin Huang, Eric A Armstrong, Alexander Chi, Kun-Tai Hsu, Deric L Wheeler, Paul M Harari Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells. Clin. Cancer Res.: 2009, 15(5);1585-92 [PubMed:19190133]
  • Gregory W Allen, Corey Saba, Eric A Armstrong, Shyh-Min Huang, Sergio Benavente, Dale L Ludwig, Daniel J Hicklin, Paul M Harari Insulin-like growth factor-I receptor signaling blockade combined with radiation. Cancer Res.: 2007, 67(3);1155-62 [PubMed:17283150] Shyh-Min Huang, Jing Li, Eric A Armstrong, Paul M Harari Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res.: 2002, 62(15);4300-6 [PubMed:12154033]
  • S L Sutor, B T Vroman, E A Armstrong, R T Abraham, L M Karnitz A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf. J. Biol. Chem.: 1999, 274(11);7002-10 [PubMed:10066754]