Randolph Ashton

Randy Ashton

Randolph Ashton

Assistant Professor, Biomedical Engineering, BIONATES

Years Active



  • B.S., Hampton University
  • Ph.D., Rensselaer Polytechnic Institute
  • Postdoctoral Fellow, University of California–Berkeley

Research Description

  • Neural tissue engineering
  • Vascular tissue engineering
  • Regenerative therapies for the central nervous system
  • Stem cell bioprocessing
  • Nanoscale biomaterials engineering
  • Engineering the stem cell-biomaterial interface


  • Biomedical Engineering Society
  • American Institute of Chemical Engineers
  • Society for Biological Engineers
  • International Society for Stem Cell Research


  • NIH Postdoctoral Fellow, National Heart Lung and Blood Institute (NHLBI), 2009
  • California Institute for Regenerative Medicine (CIRM) Postdoctoral Fellow, 2008
  • NIH-NIGMS Biomolecular Science and Engineering Training Fellow, 2004
  • Rensselaer Polytechnic Institute Dean Fellowship Recipient, 2002
  • National Consortium for Graduate Degrees for Minorities in Engineering Fellow, 2002
  • Hampton University Presidential Scholar, 1999

Selected Publications

  • Ashton RS, Conway A, Pangarkar C, Bergen J, Lim K, Shah P, Bissell M, Schaffer DV. Ephrin-B2 signaling regulates adult hippocampal neurogenesis. Nature Neuroscience (In Press)
  • Pollock JF, Ashton RS, Rode N, Schaffer DV, Healy KE. Molecular characterization of multivalent bioconjugates by size-exclusion chromatography with multi-angle laser light scattering. Bioconjugate Chem. 2012 Aug 23 [Epub ahead of print]
  • Ashton RS, Keung AJ, Peltier J, Schaffer DV (2011). Progress and Prospects in Stem Cell Engineering. Annual Review of Chemical and Biomolecular Engineering, 2: 479-502. DOI: 10.1146/annurev-chembioeng-061010-114105
  • Banerjee, A., Arha, M., Choudhary, S., Ashton, R.S., Bhatia, S.R., Schaffer, D.V., Kane, R.S. (2009). The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells. Biomaterials, 27: 4695-4699. PMCID19539367
  • Wall ST, Saha KS, Ashton RS, Kim K, Schaffer DV, Healy KE (2008). Multivalency of sonic hedgehog conjugated to linear polymer chains modulates protein potency. Bioconjugate Chem. 19: 306-312. PMCID18380472
  • Ashton RS, Banerjee A, Punyani S, Schaffer DV, Kane RS (2007). Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture. Biomaterials, 28: 5518-5525. PMCID17881048
  • Ashton RS, Peltier J, Fasano CA, O’Neill A, Leonard J, Temple S, Schaffer DV, Kane RS (2007). High-throughput screening of gene function in stem cells using clonal microarrays. Stem Cells, 25: 2928-2935. PMCID17673524
  • Rai PR, Saraph A, Ashton R, Poon V, Mogridge J, Kane RS (2007). Raftlike polyvalent inhibitors of anthrax toxin: modulating inhibitory potency by formation of lipid microdomains. Angew Chem Int Ed Engl. 46: 2207-2209. PMCID17310484
  • Gujraty KV, Ashton R, Bethi SR, Kate S, Faulkner CJ, Jennings GK, Kane RS (2006). Thiol-mediated anchoring of ligands to self-assembled monolayers for studies of biospecific interactions. Langmuir 22: 10157-10162. PMCID17107015
  • Ashton R, Padala C, and Kane RS (2003). Microfluidic separation of DNA. Curr Opin Biotechnol. 14: 497-504. PMCID14580579