Microbiomes are the communities of microorganisms that live on or in people, plants, soil, oceans, and the atmosphere. Microbiomes maintain healthy function of these diverse ecosystems, influencing human health, climate change, food security, and other factors. Although new technologies have enabled exciting discoveries about the importance of microbiomes, scientists still lack the knowledge and tools to manage microbiomes in a manner that prevents dysfunction or restores healthy function.

WID researchers are engaged in diverse microbiome projects like linking gut microbes to Alzheimers Disease and gene expression, understanding the implications of microbial diversity, and discovering new antibiotics.

The UW-Campus Microbiome Portal is a component of WID’s Multi-Omics Hub.

New Effective and Safe Antifungal Isolated from Sea Squirt Microbiome

2024-11-14T21:56:23-06:00

By combing the ocean for antimicrobials, scientists at the University of Wisconsin–Madison have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice. WID postdoc Marc Chevrette is part of the team that published the finding in Science.

New Effective and Safe Antifungal Isolated from Sea Squirt Microbiome2024-11-14T21:56:23-06:00

UW–Madison Researchers Earn Army Research Office Grant to Study Microbial Communication

2024-11-14T22:07:24-06:00

WID Director Jo Handelsman and biochemistry professor Ophelia Venturelli are part of a multi-university interdisciplinary team awarded a grant to study information transmission in microbial communities and how biological networks communicate.

UW–Madison Researchers Earn Army Research Office Grant to Study Microbial Communication2024-11-14T22:07:24-06:00

THOR Wrangles Complex Microbiomes into a Model for Improving Them

2025-01-27T14:36:51-06:00

A growing understanding of microbial communities and their influence on human health or crop productivity has led to the dream of changing these communities to produce benefits. New research at WID addresses this head-on.

THOR Wrangles Complex Microbiomes into a Model for Improving Them2025-01-27T14:36:51-06:00

You may also like … Algorithms that improve drug discovery

2024-11-14T22:18:24-06:00

WID researchers Stephen Wright and Robert Nowak are part of a UW2020: WARF Discovery Initiative project to create machine learning tools that dramatically reduce the time and cost associated with screening compounds for therapeutic relevance.

You may also like … Algorithms that improve drug discovery2024-11-14T22:18:24-06:00

Phenotypic variability and community interactions of germinating Streptomyces spores

2025-01-27T14:21:01-06:00

Systems Biology researcher Kalin Vetsigian and graduate student Ye Xu recently published findings in Nature's Scientific Reports about the stochasticity of growth within Streptomycetes spore communities.

Phenotypic variability and community interactions of germinating Streptomyces spores2025-01-27T14:21:01-06:00

Gut bugs affect DNA expression

2024-11-14T22:22:02-06:00

The podcast "Is DNA the Basis for all Life in the Universe?" produced by The Naked Scientists, an affiliate of the BBC at Cambridge University features John Denu speaking of his recent findings on how the gut microbiome affects DNA expression.

Gut bugs affect DNA expression2024-11-14T22:22:02-06:00
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