Jayaraman Tharmalingam
Integrate computational and experimental models of host-pathogen interaction in bacterial infections
Jayaraman Tharmalingam was born and brought up in a small village in Tamil Nadu, India. He has been interested in science and math since childhood and dreams of becoming a scientist. He graduated from Christian Medical College, Vellore, India, and completed his first postdoctoral research in a collaborative research project at RIKEN, Tokyo University of Science, and Chiba University, Japan. He is an interactive and friendly person who has a bunch of friends. His hobbies are reading books and traveling.
The May MIDAS lab generates and integrates multi-omics data to develop multi-scale theoretical models of host-pathogen, microbial and molecular biology systems. My research focus is on developing and integrating experimental models of host-innate and adaptive immune cells response against bacterial infection, with a focus on tuberculosis disease. Using cellular and animal models, I investigate the impact of comorbidities on host effector response and immune signaling pathways. My work also leverages confocal microscopy and genetic engineering methodologies to understand molecular to cellular scale interactions in host-pathogen systems and bacterial communities.