Last Friday morning on Wisconsin Today, a program on Wisconsin Public Radio, Jo Handelsman, Director of the Wisconsin Institute for Discovery (WID), examined the potential impact of proposed federal research cuts. In this 13-minute talk, Handelsman discussed how the National Institutes of Health (NIH) had been considering a directive to cap overhead costs at 15 percent, a move that could cost the University of Wisconsin–Madison at least $62 million annually. Her remarks provide valuable insight into how the Trump Administration’s plan to reduce federal funding for medical research could affect UW–Madison laboratories and the broader scientific community.