Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. This approach will allow doctors and researchers to predict more accurately which treatment and prevention strategies for a particular disease will work in which groups of people. It is in contrast to a “one-size-fits-all” approach, in which disease treatment and prevention strategies are developed for the average person, with less consideration of the differences between individuals.

Researchers at WID with expertise in complex biological systems, epigenetics, data science, health care, gene editing, and tissue engineering will contribute to “healthy people” initiatives through precison medicine.

Precision medicine is an important component of WID’s Multi-Omics Hub.

Micro-Molded ‘Ice Cube Tray’ Scaffold is Next Step in Returning Sight to Injured Retinas

2024-11-14T21:49:43-06:00

WID's Sarah Gong is part of a team that developed a micro-molded scaffolding photoreceptor "patch" to be implanted under damaged or diseased retinas, the next step in restoring sight.

Micro-Molded ‘Ice Cube Tray’ Scaffold is Next Step in Returning Sight to Injured Retinas2024-11-14T21:49:43-06:00

Randolph Ashton and Collaborators Win WARF Innovation Award

2024-11-14T21:54:52-06:00

WID's Randolph Ashton, Gavin Knight, Benjamin Knudsen, and Nisha Iyer take top honors from the Wisconsin Alumni Research Foundation's Innovation Awards. Their work, Superior Neural Tissue Models for Disease Modeling, Drug Development and More, was selected from more than 400 innovation disclosures.

Randolph Ashton and Collaborators Win WARF Innovation Award2024-11-14T21:54:52-06:00

New Effective and Safe Antifungal Isolated from Sea Squirt Microbiome

2024-11-14T21:56:23-06:00

By combing the ocean for antimicrobials, scientists at the University of Wisconsin–Madison have discovered a new antifungal compound that efficiently targets multi-drug-resistant strains of deadly fungi without toxic side effects in mice. WID postdoc Marc Chevrette is part of the team that published the finding in Science.

New Effective and Safe Antifungal Isolated from Sea Squirt Microbiome2024-11-14T21:56:23-06:00

UW Researchers Devise Approach to Treat Rare, Incurable Form of Blindness

2024-11-14T21:58:38-06:00

WID's Kris Saha was among UW–Madison researchers who have published a proof-of-concept method to correct an inherited form of macular degeneration that causes blindness, and that is currently untreatable.

UW Researchers Devise Approach to Treat Rare, Incurable Form of Blindness2024-11-14T21:58:38-06:00

New Tool for Assessing Heart Muscle Cells Helps Unlock Their Potential

2024-11-14T21:59:49-06:00

A team of UW-Madison researchers led by Discovery Fellow Wendy Crone has created a powerful tool to help assess what experimental factors help to produce stem cell-generated cardiomyocytes that behave like adult heart cells.

New Tool for Assessing Heart Muscle Cells Helps Unlock Their Potential2024-11-14T21:59:49-06:00

Tiny Capsules Packed with Gene-Editing Tools Offer Alternative to Viral Delivery of Gene Therapy

2024-11-14T22:05:28-06:00

An interdisciplinary pair of WID researchers has developed a new nanocapsule delivery method for delivering the CRISPR-Cas9 gene editing tool. The new system could be used for many types of gene therapies.

Tiny Capsules Packed with Gene-Editing Tools Offer Alternative to Viral Delivery of Gene Therapy2024-11-14T22:05:28-06:00

Uncovering a Connection Between Regulators and Genes During Early Neurodevelopment

2025-01-27T14:18:51-06:00

WID researchers used a collaborative combination of computational and wet lab experimental techniques to find a connection between a transcription factor and a neurodevelopment gene.

Uncovering a Connection Between Regulators and Genes During Early Neurodevelopment2025-01-27T14:18:51-06:00

UW Carbone Scientists Present at Annual Cancer Research Conference

2024-11-14T22:11:58-06:00

One of the UW Carbone Cancer Center members presenting is WID's Peter Lewis. His work focuses on how genes are turned on and off during embryonic development, and how misregulation in those genes can lead to some childhood cancers.

UW Carbone Scientists Present at Annual Cancer Research Conference2024-11-14T22:11:58-06:00

Randolph Ashton Continues Research into Causes of Lou Gehrig’s Disease

2024-11-14T22:15:22-06:00

In August 2017, Randolph Ashton received almost $800,000 from the National Institute of Neurological Disorders and Stroke, part of NIH, to continue a five-year research study of Lou Gehrig’s disease (amyotrophic lateral sclerosis, or ALS), after successfully completing its first phase.

Randolph Ashton Continues Research into Causes of Lou Gehrig’s Disease2024-11-14T22:15:22-06:00

The “Icing” on the DNA

2024-11-14T22:16:54-06:00

Xuehua Zhong recently received an outstanding investigator award from NIH via the Maximizing Investigators' Research Award (MIRA) mechanism to support her research. She talked about how she uses plants to study epigenetics in an interview with Grow magazine.

The “Icing” on the DNA2024-11-14T22:16:54-06:00

Connecting the Dots: a New Method to Understand Cell Type Transitions

2025-01-27T14:49:18-06:00

Wisconsin Institute for Discovery (WID) researchers Rupa Sridharan and Sushmita Roy are combining their expertise in regenerative biology and computational biology to better understand how cells transition from one type to another through gene regulation.

Connecting the Dots: a New Method to Understand Cell Type Transitions2025-01-27T14:49:18-06:00

Machine Learning Can Detect a Genetic Disorder from Speech Recordings

2024-11-14T22:17:35-06:00

Machine learning is a form of artificial intelligence by which algorithms are "trained" to analyze new information using existing data. Researchers are using it to identify individuals with a genetic condition known as fragile X premutation.

Machine Learning Can Detect a Genetic Disorder from Speech Recordings2024-11-14T22:17:35-06:00

You may also like … Algorithms that improve drug discovery

2024-11-14T22:18:24-06:00

WID researchers Stephen Wright and Robert Nowak are part of a UW2020: WARF Discovery Initiative project to create machine learning tools that dramatically reduce the time and cost associated with screening compounds for therapeutic relevance.

You may also like … Algorithms that improve drug discovery2024-11-14T22:18:24-06:00
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