Chevrette Lab

Pinwheel with 5 petals. Center is Evolution of Secondary Metabolism. Petals are Evolution of Biosynthetic Genes, Evolution of Biosynthetic Pathways, Community Dynamics, New Antibiotics & Chemistry, and Microbiome Interactions.

The Chevrette lab studies the molecular and ecological roles of bacterial secondary metabolites—specialized small molecules that mediate microbial interactions and serve as sources of therapeutics like antibiotics and anticancer agents. We investigate how biosynthetic gene clusters (BGCs) are regulated, evolve, and function within microbial genomes and communities. Using a combination of comparative genomics, transcriptomics, metabolomics, and synthetic biology, we explore how bacteria coordinate chemical communication and competition in diverse environments, including host-associated microbiomes. Our long-term goal is to build predictive models of microbial interactions and harness microbial chemistry for biomedical and ecological applications.
CHEVRETTE LAB WEBSITE

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Pinwheel with 5 petals. Center is Evolution of Secondary Metabolism. Petals are Evolution of Biosynthetic Genes, Evolution of Biosynthetic Pathways, Community Dynamics, New Antibiotics & Chemistry, and Microbiome Interactions.

The Chevrette lab studies the molecular and ecological roles of bacterial secondary metabolites—specialized small molecules that mediate microbial interactions and serve as sources of therapeutics like antibiotics and anticancer agents. We investigate how biosynthetic gene clusters (BGCs) are regulated, evolve, and function within microbial genomes and communities. Using a combination of comparative genomics, transcriptomics, metabolomics, and synthetic biology, we explore how bacteria coordinate chemical communication and competition in diverse environments, including host-associated microbiomes. Our long-term goal is to build predictive models of microbial interactions and harness microbial chemistry for biomedical and ecological applications.
CHEVRETTE LAB WEBSITE

All Labs