Tag: epigenetics
Epigenetics researchers at WID examine how the epigenome — the layer of chemical information that sits on top of the genome — switches genes ‘on’ or ‘off’ and is controlled by outside factors such as lifestyle and diet. Research in this area focuses on the molecular, chemical, and physical components underlying epigenetic mechanisms and utilizes genomic, proteomic, and biochemical methods to reveal novel epigenetic information and mechanisms. We are investigating how extrinsic factors (diet, small-molecules, metabolism and environmental factors) influence the epigenome and control cellular decision and are developing new technologies to uncover and interrogate the epigenetic code written in chemical tags.
As part of WID’s Multi-Omics Hub, the Epigenetics Initiative reaches out to foster interdisciplinary collaborations with basic and translational research in epigenetics and chromatin function.
Cindy Liu
CRISPR-mediated knock-ins of Polycomb-associated DNA elements in Arabidopsis thaliana
Harshini Cormaty
Epigenetic mechanisms that control Primordial Germ Cell differentiation in mice
Molecular Puzzles in 3D: Understanding a Mechanism for Methylation
A new publication from the Xuehua Zhong’s group at the Wisconsin Institute for Discovery and the genetics department at the University of Wisconsin–Madison clarifies an important epigenetic mechanism in plants that will help researchers better understand the epigenomes of both plants and animals.
Nan (Yifang) Jiang
Functions of human coronaviruses defective genomes on the range and severity of diseases.
Saptarshi Pyne
Development of computational methods for inference and analysis of biological networks
Myra Mohammad
Virus-host interactions and proofreading mechanisms in coronaviruses
Jose Moran
Mechanistic studies on catalysis and regulation of SIRT6 deacetylation on nucleosomal substrates
Sridharan Earns Vilas Faculty Mid-Career Investigator Award
Rupa Sridharan was among 24 UW professors to earn Vilas professorships and awards. The Vilas Faculty Mid-Career Investigator Award recognizes research and teaching excellence and provides flexible research funding for three years.
Xiaoya Zhang
Epigenetic control of cell identity in development and somatic cell reprogramming.
Science Outreach: A Versatile Training Tool
Genetics professor Xuehua Zhong is a true believer in the power of outreach to instill a love of science in young people and develop mentoring skills in her students. To her delight, she has found an opportunity to do both.
Deep in the Weeds
Xuehua Zhong’s close study of an ordinary plant’s cellular mechanisms could lead to big advances in agriculture and medicine. Zhong is featured in Grow magazine.
Ryan Herringa
Associate Professor
Neurodevelopmental mechanisms of stress and mental illness in youth