| Project | Started | |||
|---|---|---|---|---|
| A CRISPR/Cas9 Based Therapeutic Strategy for Alzheimer’s Disease | Subhojit Roy (PI) Shaoqin (Sarah) Gong (co-PI) Krishanu Saha (co-PI) | Wisconsin Alumni Research Foundation | Department of Anatomic Pathology | 2017 |
| A Novel Direction in Mixed Integer Polynomial Optimization: Structural Properties, Polyhedral Approximations, and Global Optimization Algorithms | Alberto Del Pia (PI) Silvia Di Gregorio | National Science Foundation | Data Science Hub | 2017 |
| A Virtual Tour Through Mount Horeb Area History | Kevin Ponto (PI) Ross Tredinnick (PI) | Raymond and Margaret Vicker Charitable Trust | 2017 | |
| Alfred Toepfer Faculty Fellow Award | Xuehua Zhong (PI) | University of Wisconsin Foundation | 2016 | |
| An Endothelium-Protective Stent-Free Strategy for Mitigation of Intimal Hyperplasia After Vascular Surgery | Shaoqin (Sarah) Gong (PI) Craig Kent (PI) Lian-Wang Guo (PI) | DHHS National Institutes of Health | Department of Biomedical Engineering | 2018 |
| Analyzing the Impact of Virtual Reality and 3D Capture Technology on Crime Scene Investigation | Kevin Ponto (PI) Ross Tredinnick Simon Smith | Department of Justice | 2017 | |
| Assembly of Novel Gene Editing Particles to Understand Genome Surgery in Patient-Derived Cells | Krishanu Saha (PI) Amr Abdeen | DHHS National Institutes of Health | 2016 | |
| BIGDATA: Human and Machine Co-Processing | Robert Nowak (PI) Stephen Wright (Co-PI) Michael O’Neill Michael O’Neill | National Science Foundation | 2014 | |
| Bioengineering Micro-Patterned Scaffolds for Human Pluripotent Stem Cell-Based Photoreceptor Replacement Therapies | David Gamm (PI) Zhenqiang Jack Ma (co-PI) Shaoqin (Sarah) Gong (co-PI) | Foundation For Fighting Blindness | Wasiman Center | 2016 |
| Brain Comp Infra: Workshop: Research Methods and Infrastructure for Scalable Computing in Neuroscience | Lauren Michael (PI) | National Science Foundation | Data Science Hub | 2016 |
| CAREER: Comparative Network Biology to Study the Evolution of Regulatory Networks | Sushmita Roy (PI) Alireza Fotuhi Siahpirani Sara Knaack Christina Koch | National Science Foundation | Department of Biostatistics and Medical Informatics | 2014 |
| CAREER: Engineering Human CNS Morphogenesis Ex Vivo: Spinal Cord | Randolph Ashton (PI) Carlos Marti-Figueroa | National Science Foundation | Department of Biomedical Engineering | 2017 |
| CAREER: Modeling Made Easy | Laurence Loewe (PI) | National Science Foundation | 2012 | |
| CAREER: Molecular Dissection of Arabidopsis DNA Methylation Mechanism | Xuehua Zhong (PI) Xiangsong Chen Jianjun Jiang | National Science Foundation | Laboratory of Genetics | 2015 |
| CAREER: Towards Synthetic Biology in Human Stem Cells | Krishanu Saha (PI), | National Science Foundation | Department of Biomedical Engineering | 2014 |
| Chromatin Remodeling and Signaling Pathways | Rupa Sridharan (PI) Zafirah Zaidan | DHHS National Institutes of Health | 2015 | |
| Clustering of Time Series for Usage-Based Insurance | American Family Insurance | Data Science Hub | 2018 | |
| CNF-Based Large-Area High-Performance Flexible Electronics | Zhenqiang Jack Ma (PI) Shaoqin (Sarah) Gong (co-PI) | US Endowment for Forestry and Communities | Department of Biomedical Engineering | 2017 |
| Computational approaches for comparative regulatory genomics to decipher long range gene regulation | Sushmita Roy (PI) | DHHS National Institutes of Health | Department of Biostatistics and Medical Informatics | 2018 |
| Computational Inference of Regulatory Network Dynamics on Cell Lineages | Sushmita Roy (PI) Rupa Sridharan (Co-PI) Alireza Fotuhi Siahpirani Sara Knaack Shilu Zhang | DHHS National Institutes of Health | 2016 | |
| CRII: CIF: Universal Analysis of Optimization Algorithms | Laurent Lessard (PI) Saman Cyrus Akhil Sundararajan | National Science Foundation | Data Science Hub Department of Electrical and Computer Engineering | 2017 |
| Design of a Database for Graduate Education in Data Analytics | Jo Handelsman (PI) Josh Pultorak | Alfred P. Sloan Foundation | Multi-Omics Hub | 2017 |
| Development and Preclinical Testing of Multifunctional Nanoparticles for Optimizing the In Situ Tumor Vaccine Effect of Radiation Therapy | Zachary Morris (PI) Shaoqin (Sarah) Gong (co-PI) | Wisconsin Alumni Research Foundation | Department of Biomedical Engineering Department of Oncology | 2019 |
| Development of Unimolecular Nanoparticle-Mediated Periadventitial Drug Delivery System for Sustained and Targeted Inhibition of Intimal Hyperplasia Following Open Vascular Reconstruction | Shaoqin (Sarah) Gong (PI) Craig Kent (PI) Lian-Wang Guo (PI) Yuyuan Wang | DHHS National Institutes of Health | Department of Surgery | 2016 |
| Dissecting Molecular Mechanisms of Astrocyte-Neuron Interaction in Rett Syndrome Using Arrays of Gene-Edited, Patient-Derived Cells | Krishanu Saha (PI) Kaivalya Molugu Alireza Aghayee | Brain and Behavior Research Foundation | 2017 | |
| EAGER: A Microscale Testbed to Assay and Manufacture CAR T-Cell Immunotherapies | Krishanu Saha (PI) Katie Mueller Nicole Piscopo | National Science Foundation | 2016 | |
| Elucidating Mechanisms of Chromatin Dysregulation by Oncohistones in Pediatric Cancers | Peter Lewis (PI) | Kimmel Foundation | Multi-Omics Hub | 2015 |
| Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain | Shaoqin (Sarah) Gong (PI) Marina Emborg (co-PI) Jon Levine (co-PI) Subhojit Roy (co-PI) Krishanu Saha (co-PI) | DHHS National Institute of Neurological Disorders and Stroke National Institutes of Health | Department of Biomedical Engineering Department of Pathology and Laboratory Medicine Medical Physics Primate Center | 2018 |
| EPCN: Robust Control Architectures for Decentralized Uncertain Systems | Laurent Lessard (PI) | National Science Foundation | Data Science Hub | 2017 |
| Epigenetic Regulation and Agricultural Productivity | Xuehua Zhong (PI) | Hatch Act Formula Fund | Laboratory of Genetics | 2016 |
| Ethnography of Home Security | Robert Nowak (PI) | American Family Insurance | Data Science Hub | 2016 |
| Evolution of Virus-Host Interactions | John Yin (PI) Paul Turner (Yale University) (co-PI) Huicheng Shi | DHHS National Institutes of Health | Department of Chemical and Biological Engineering | 2010 |
| Explanation-Based Active Learning | Robert Nowak (PI) | American Family Insurance | Data Science Hub Department of Electrical and Computer Engineering | 2018 |
| Exploring the Universe from Antarctica | Kevin Ponto (PI) Ross Tredinnick | National Science Foundation | Data Science Hub | 2016 |
| High-Throughput Modeling of ALS Using iPSC-Derived Neural Tube Microarrays | Randolph Ashton (PI) David Beebe (co-PI) Gavin Knight Carlos Marti-Figueroa | DHHS National Institutes of Health | 2014 | |
| Human Models for Analysis of Pathways Center | Randolph Ashton (co-PI) Sushmita Roy (co-PI) Krishanu Saha (Co-PI) | Environmental Protection Agency | Department of Orthopedics and Rehabilitation | 2014 |
| Inference for Autoregressive Point Processes | Garvesh Raskutti (co-PI) | National Geospatial-Intelligence Agency | Data Science Hub | 2017 |
| Inference for High-Dimensional Self-Exciting Point Processes | Garvesh Raskutti (co-PI) | Department of Defense - Army | Data Science Hub | 2017 |
| Informing Great Lakes Connectivity Decisions: An Enhanced Online Portal for High-Resolution Barrier Data and Species-Specific Benefit Analyses | Peter Mcintyre (PI) Michael Ferris (co-PI) Jeffrey Dischler Steven Wangen | Great Lakes Fishery Trust | Center for Limnology | 2015 |
| Institute for Foundations of Data Science | Stephen Wright (PI) Robert Nowak (co-PI) | National Science Foundation | Data Science Hub | 2017 |
| Integration of Modern Convex and Integer Optimization Approaches in Stochastic Mixed-Integer Programming | Jim Luedtke (PI) Stephen Wright (co-PI) Jeff Linderoth (co-PI) | National Science Foundation | Data Science Hub | 2016 |
| Interactions and Community Dynamics in Multi-species Communities of Soil Bacteria | Kalin Vetsigian (PI) Sailendharan Sudakaran | National Science Foundation | 2015 | |
| Investigating energy, efficiency, information processing and control architectures of microbial community interaction networks | Jo Handelsman (PI) Ophelia Venturelli (Co-PI) | University of Southern California (MURI) | 2019 | |
| Investigating the Epigenetic Nature of Chromatin States | Peter Lewis (PI) | Pew Charitable Trust | Department of Biomolecular Chemistry | 2016 |
| Linking Mitochondrial Variation and Lifespan Amongst Five Species of Rodentia | John Denu (PI) | DHHS National Institutes of Health | Multi-Omics Hub | 2016 |
| Mathematical Foundations of Secure Computing Clouds | Robert Nowak (PI) Stephen Wright (Co-PI) Jordan Ellenberg (co-PI) | Department of Defense - Air Force | Data Science Hub | 2013 |
| Mechanisms and Environmental Determinants of Rhinovirus Illness Severity | Ann Palmenberg (PI) John Yin (co-PI) Huicheng Shi | DHHS National Institutes of Health | Department of Pediatrics | 2013 |
| Mixed-Integer Quadratic Optimization: Algorithms and Complexity | Alberto Del Pia (PI) | Department of Defense - Navy | 2019 | |
| Network-Enabled Optimization System (NEOS) | Michael Ferris (PI) Michelle Craft | Morgridge Institute for Research | 2010 | |
| Oncohistones: Role of Histone H3 Mutations in the Oncogenesis of Pediatric Cancer | Peter Lewis (PI) Aayushi Jain Siddhant Jain | National Institutes of Health | Department of Biomedical Engineering | 2015 |
| Organoid Microarrays for pan-Hindbrain and Spinal Cord Screening | Randolph Ashton (PI) Nisha Iyer Gavin Knight | Burroughs Wellcome | 2014 | |
| Performance Evaluation of Light-Weight Triaxial Biocomposites | Shaoqin (Sarah) Gong (PI) | Forest Service US Department of Agriculture | Department of Biomedical Engineering | 2013 |
| Peripheral Nerve-On-A-Chip for Predictive Preclinical Pharmaceutical Testing | AxoSim | Department of Biomedical Engineering | 2018 | |
| Physical and Chemical Origins of Life | John Yin (PI) | Wisconsin Alumni Research Foundation | 2015 | |
| Role of Higher-Order Interactions for Stability of Microbial Communities | Kalin Vetsigian (PI) Seyfullah Kotil Ye Xu | Simons Foundation | 2015 | |
| Role of Histone Modifying Enzymes in Tumorigenesis | Rupa Sridharan (PI) | Kimmel Foundation | Department of Cell and Regenerative Biology | 2015 |
| Shaw Scientist Award | Peter Lewis (PI) | Greater Milwaukee Foundation | Department of Biomolecular Chemistry | 2015 |
| Shaw Scientist Award | Rupa Sridharan (PI) | Greater Milwaukee Foundation | 2013 | |
| SI2-SSI: Pegasus: Automating Complete and Data Intensive Science | Miron Livny (PI) | University of Southern California (NSF) | Data Science Hub | 2017 |
| Single Cell Profiling To Define Biomarkers Of Photoreceptor Dysfunction After Gene Editing Within IPSC-Derived Organoids | Krishanu Saha (PI) Sushmita Roy (co-PI) David Gamm (co-PI) Melissa Skala (co-PI) | DHHS National Institutes of Health | Department of Biomedical Engineering Department of Cell and Regenerative Biology Department of Pediatrics | 2018 |
| Targeted Therapy of Neuroendocrine Cancers via the Notch Signaling Pathway | Shaoqin (Sarah) Gong (PI) | DHHS National Institutes of Health | Department of Biomedical Engineering | 2013 |
| Targeted Treatment for Pulmonary Hypertension Associated with Congenital Diaphragmatic Hernia | David McCulley (PI) Shaoqin (Sarah) Gong (co-PI) | Institute for Clinical and Translational Research at UW-Madison | Department of Pediatrics | 2017 |
| Targeting Triple Negative Breast Cancer Using Nanoparticles Loaded with the Anti-Cancer Drug Aminoflavone | Shaoqin (Sarah) Gong (PI) Wei Xu (PI) | DHHS National Institutes of Health | Department of Oncology | 2016 |
| The Multifaceted Mathematics Center for Complex Energy Systems | Michael Ferris (PI) Jeff Linderoth (co-PI) Jim Luedtke (co-PI) Stephen Wright (co-PI) Bernard Lesiutre (co-PI) Chris DeMarco (co-PI) Victor Zavala (co-PI) Clément Royer Carla Michini Ching-pei Lee | Argonne National Laboratory (Department of Energy) | Data Science Hub | 2012 |
| Tiny Earth | Jo Handelsman (PI) Josh Pultorak | American Society for Microbiology University of Connecticut Wisconsin Institute for Discovery | 2012 | |
| Tiny Earth Advanced: A Research Course Series | Jo Handelsman (PI) | Howard Hughes Medical Institute | 2019 | |
| Tiny Earth Database Project | Jo Handelsman (PI) | Alfred P. Sloan Foundation | Illuminating Discovery Hub | 2017 |
| Tiny Earth Wisconsin Partner Instructor Training and Supporting Community Engagement | Jo Handelsman (PI) | Silicon Valley Community Foundation | 2018 | |
| Uncovering the Epigenetic Codes for Genome Integrity and Environmental Interaction | Xuehua Zhong (PI) Shuiming Qian | DHHS National Institutes of Health | Multi-Omics Hub | 2017 |
| Using an Evolutionary Framework to Study Robustness and Predictive Power of Data-Driven Molecular Regulatory Networks | Sushmita Roy (PI) Sara Knaack Junha Shin | James S McDonnell Foundation | Data Science Hub | 2016 |