Dawid Maciorowski
MD-PhD Candidate
Novel CRISPR-based gene editing strategies to investigate treatments for pediatric cancer
The advent of the CRISPR-CAS9 technique gives researchers the ability to make precise changes to the DNA of, theoretically, any living organism that has DNA. That precision is particularly meaningful for treatment of diseases caused by well-known faults in genes — otherwise incurable diseases such as sickle cell anemia, the fatal lung disorder cystic fibrosis, and the blindness-causing Leber congenital amaurosis. CRISPR-Cas9 could be a way to prevent or reverse those disorders.
MD-PhD Candidate
Novel CRISPR-based gene editing strategies to investigate treatments for pediatric cancer
Integrate computational and experimental models of host-pathogen interaction in bacterial infections
CRISPR-mediated knock-ins of Polycomb-associated DNA elements in Arabidopsis thaliana
Mechanism that links neurodegenerative diseases to lysosomal and endosomal dysfunction.
WID and Saha Lab alumnus, and current postdoc at the Morgridge Institute for Research, Amritava Das anticipates that he will put his engineering and bioscience training to use exploring the sometimes knotty connections between science, national security, and finance.
Shaoqin “Sarah” Gong collaborates on a new approach to target genetic mutations and develop a new therapy for restoring vision in children and adults.
Functions of human coronaviruses defective genomes on the range and severity of diseases.
A promising platform developed by the Saha Lab at WID advances the CRISPR genome editing field and could lead to effective treatments for many diseases.
WID’s Kris Saha was among UW–Madison researchers who have published a proof-of-concept method to correct an inherited form of macular degeneration that causes blindness, and that is currently untreatable.
WID’s Kris Saha spoke to Wisconsin Public Radio to answer questions about gene editing technology CRISPR in response to a question received by WHYsconsin.
The the MS Biotechnology program at UW and the Wisconsin Institute for Discovery are partnering to screen the documentary film “Human Nature”, an exploration of gene editing and its implications both biological and ethical.