Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. This approach will allow doctors and researchers to predict more accurately which treatment and prevention strategies for a particular disease will work in which groups of people. It is in contrast to a “one-size-fits-all” approach, in which disease treatment and prevention strategies are developed for the average person, with less consideration of the differences between individuals.
Researchers at WID with expertise in complex biological systems, epigenetics, data science, health care, gene editing, and tissue engineering will contribute to “healthy people” initiatives through precison medicine.
Precision medicine is an important component of WID’s Multi-Omics Hub.
WID’s Kris Saha was among UW–Madison researchers who have published a proof-of-concept method to correct an inherited form of macular degeneration that causes blindness, and that is currently untreatable.
A team of UW-Madison researchers led by Discovery Fellow Wendy Crone has created a powerful tool to help assess what experimental factors help to produce stem cell-generated cardiomyocytes that behave like adult heart cells.
WID’s Kris Saha spoke to Wisconsin Public Radio to answer questions about gene editing technology CRISPR in response to a question received by WHYsconsin.
The the MS Biotechnology program at UW and the Wisconsin Institute for Discovery are partnering to screen the documentary film “Human Nature”, an exploration of gene editing and its implications both biological and ethical.
WID researchers have developed a computational tool that can accurately predict the three-dimensional interactions between regions of human chromosomes.
Xuehua Zhong’s close study of an ordinary plant’s cellular mechanisms could lead to big advances in agriculture and medicine. Zhong is featured in Grow magazine.
An interdisciplinary pair of WID researchers has developed a new nanocapsule delivery method for delivering the CRISPR-Cas9 gene editing tool. The new system could be used for many types of gene therapies.
WID graduate student Arezoo Movaghar was a collaborator in a study that employed machine learning to mine decades of electronic health records of nearly 20,000 individuals.
Assistant Professor
My research involves the development of statistical models to answer biological questions.
Researchers at the Wisconsin Institute for Discovery are co-Principal Investigators and co-Investigators on four UW2020: WARF Discovery Initiative projects.
WID researchers used a collaborative combination of computational and wet lab experimental techniques to find a connection between a transcription factor and a neurodevelopment gene.
Associate Professor
Neurodevelopmental mechanisms of stress and mental illness in youth
CRISPR-Cas9 Strategy to Generate DOT1L-Deficient Embryonic Stem Cells to Study Pluripotency
WID’s Tom Turng envisions a future in which surgeons can order mass-produced artificial blood vessels that arrive ready to use in bypass surgeries.
WID seeks to add to its roster of excellent faculty with two new hires in emerging cutting-edge fields.
WID’s new hubs—Data Science, Multi-Omics, and Illuminating Discovery—represent a new path forward for collaborative research projects and fields.
A paper published in eLife this week by an interdisciplinary team at WID describes new methods for reproducibly manufacturing brain and spinal cord organoids with strict control over morphogenic and developmental processes.
A second WID-led team joins NIH’s Somatic Cell Genome Editing Consortium with a grant to study new methods of delivering the CRISPR/Cas9 system to the brain.
Lab Manager
Genomic DNA sequencing and viral production. Facilitate various administrative functions.
Investigators from WID are among the recipients of the latest round of UW2020 awards.
WID Director
Genetic and biochemical processes underlying interactions within plant and human microbiomes.
